Endocrine Abstracts

Introduction: Anti-Müllerian Hormone (AMH) is a useful marker of ovarian reserve (OR), since it remains stable inter/intra-cycles and presents a good correlation with ultrasonographic antral follicular count. Obesity/overweight are increasing and may affect the reproductive health. However, previous studies regarding the effect of body mass index (BMI) on AMH levels are discordant. Our main goal was to evaluate the influence of BMI in AMH levels in women with infertility....

Background and aims: Hypoglycemia is a common complication of diabetes treatment and it’s associated with poor outcomes. A link between severe hypoglycemia and renal dysfunction was suggested. No studies evaluated the impact of hypoglycemia of inpatients in microvascular or macrovascular complications. The aim of our work was to study the evolution of renal function between admission and final visit, and the impact of nephropathy in the presence of hypoglycemia in inpatie...

Introduction: Prevalence of hypothyroidism is 2–5% in women in the reprodutive age group. Hypothyroidism can affect fertility due to anovulatory cycles, luteal phase defects, hyperprolactinemia and sex hormones imbalance. Some data also report that TSH levels are inversely proportional to the fertilization rate at ART (assisted reproductive technologies).Objective: To evaluate if a relationship exists between pregnancy rates in women undergoing ...

Introduction: The deleterious effects of obesity on spontaneous reproduction are well recognized, although the literature on obesity and assisted reproductive technology outcome remains heterogeneous and inconsistent.Objective: To estimate the effect of BMI on ovarian stimulation response and live birth in women underwent in vitro fertilization (IVF).Methods: Retrospective observational study that included women submitted ...

Current lifestyle, characterized by physical inactivity and a poor diet, is heavily linked with an increased incidence of metabolic diseases. One of the most serious silent co-morbidities of those diseases is infertility. The hormonal link between food intake and energy homeostasis is mediated by the leptin ghrelin axis. Compelling evidence suggests that direct leptin’s action regulates cellular glucose homeostasis and mitochondrial biogenesis. We have recently shown that...

Introduction: Hyperglycemia (irrespective of the presence of diabetes) has been associated with worse outcomes in hospitalized patients with a variety of diseases, namely critical illness. It is been recently proposed that a relative hyperglycemia – Stress Hyperglycemia Ratio (SHR) – might be even better associated with disease outcomes. We studied how SHR correlated with various morbidity parameters in hospitalized patients due to acute pyelonephritis.<p class="...

Introduction: Spontaneous fertility in Turner syndrome (TS) is rare, due to low or absent ovarian reserve. A greater number of ovarian follicules is present in the cases of gonadal mosaicism, although the accelerated pace of apoptosis remains. Thus, the early referral to reproductive counseling is advisable, ideally soon after diagnosis. The criopreservation of oocytes is one of the options for fertility preservation. The authors present a series of 7 patients with TS admitted...

Background: Fine-needle aspiration (FNA) is an important test for triaging patients with thyroid nodules and differentiating benign from malignant disease. According to Bethesda System Classification, the rate of AUS/FLUS is between 3–6% of all FNA. The malignancy risk is of 5–15%. TSH levels might be associated to the likelihood of malignancy in thyroid nodules according to some studies. Our aim was to establish a possible correlation between TSH level and malignanc...

Hyponatremia is a common disorder, especially among the elderly, and an important morbidity and mortality cause. Empty sella syndrome, on the other hand, is a rare entity, more common in women between their fourth and sixth decade of life, and endocrine dysfunction has been reported in 10–60% of the cases. A 68-year-old man, with a past medical history of essential hypertension and glaucoma, presented at the emergency room due to malaise, asthenia, somnolence and anorexi...

Introduction: Grave´s disease (GD) is the most prevalent cause of hyperthyroidism, leading to inflammation of the thyroid gland and sometimes to an enlargement of the nearest lymph nodes caused by that same inflammatory process. Peripheral lymphadenopathy of doubtful cause presents a diagnostic dilemma. There are many potential causes: biopsy is sometimes the best way to reach a definitive diagnosis. Tuberculous adenitis is usually regional and mainly affects nodes of the...